Structure of PDB 8hsj Chain E

Receptor sequence
>8hsjE (length=361) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence]
RLVKGYLEISQDGYGFLTENLHNLESRVAIVSAGLIKQYALRAGDYVVGQ
ARPPRENERYATLLKVEAVNNLDPEAAKNRPRFDELTPQFPDRQIRLETT
PDELSTRVIDLLAPIGRGQRGLIVAPPKAGKTTLLKKIANAVLKNEPDIK
VIVLLIDERPEEVTDFRESVQGAEVIASTFDEPPQNHIRVAEFVHERAKR
IVEEGGHVMILLDSITRLARANNLVTPPTGRTLSGGLDSAALYFPKRFLG
AARNIRGGGSLTILATALVETGSRMDDVIFEEFKGTGNMELHLSRRLEER
RIFPAIDILKSGTRREELLLGEEVTHKMWLLRKVLADMDPAEAMEMLLAR
LARTKNNKEFL
3D structure
PDB8hsj Structural basis of the transcription termination factor Rho engagement with transcribing RNA polymerase from Thermus thermophilus.
ChainE
Resolution3.6 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 3.6.4.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP E G189 K190 T191 T192 E217 R218 E221 D272 S273 R276 L327 F362 G130 K131 T132 T133 E158 R159 E162 D213 S214 R217 L268 F303
BS02 BEF E P186 K187 K190 P127 K128 K131
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0004386 helicase activity
GO:0005524 ATP binding
GO:0008186 ATP-dependent activity, acting on RNA
GO:0016787 hydrolase activity
GO:0016887 ATP hydrolysis activity
Biological Process
GO:0006353 DNA-templated transcription termination

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:8hsj, PDBe:8hsj, PDBj:8hsj
PDBsum8hsj
PubMed36753546
UniProtQ5SJE9

[Back to BioLiP]