Structure of PDB 8h8e Chain E

Receptor sequence
>8h8eE (length=289) Species: 8364 (Xenopus tropicalis) [Search protein sequence]
VRFSRTCLKNFFSVLLILVYLLLMGVAVFLVYQTITDFRDKLKHPVMSVS
YKEVNMYDAPGIALYPGKARLLSCEHHWYDHIPPLKDPGQPGENTCVTQD
ISYIDPYTNKTMKHALIVQGPRDVRRRELVFLQFHLNETKQDFSAIDYLL
FSSYEAFLKSHDQVKFMQDCESSFSSWKFSGGFRTWVKMSLVKTKEEDGS
QSVEFRQETSVVNFIDRRETPDKGDQLFFVVFEWKDPYIQEIQDIITANP
WSMIALLCSVFLVLFKAADFAKLSVKWMIKVRRRHLKKR
3D structure
PDB8h8e Structure of the dimeric Xenopus tropical acid-sensitive outwardly rectifying channel ASOR trimer bound with tRNA (closed state)
ChainE
Resolution3.81 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 rna E R57 R338 R344 R2 R283 R289
Gene Ontology
Molecular Function
GO:0005254 chloride channel activity
GO:0061797 pH-gated chloride channel activity
Biological Process
GO:0006821 chloride transport
GO:0034220 monoatomic ion transmembrane transport
GO:1902476 chloride transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0034707 chloride channel complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:8h8e, PDBe:8h8e, PDBj:8h8e
PDBsum8h8e
PubMed38942816
UniProtQ0V9Z3|PACC1_XENTR Proton-activated chloride channel (Gene Name=pacc1)

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