Structure of PDB 8h3h Chain E

Receptor sequence
>8h3hE (length=528) Species: 9606 (Homo sapiens) [Search protein sequence]
SVRFDSVGGLSNHIAALKEMVVFPLLYPEVFEKFKIQPPRGCLFYGPPGT
GKTLVARALANECSQGDKRVAFFMRKGADCLSKWVGESERQLRLLFDQAY
QMRPSIIFFDQIDGLAPVRSSRQDQIHSSIVSTLLALMDGLDSRGEIVVI
GATNRLDSIDPALRRPGRFDREFLFSLPDKEARKEILKIHTRDWNPKPLD
TFLEELAENCVGYCGADIKSICAEAALCALRRRYPQIYTTSEKLQLDLSS
INISAKDFEVAMQKMIPASQRAVTSPGQALSTVVKPLLQNTVDKILEALQ
RVFPHAEYQPMSFRPRILIVGEPGFGQGSHLAPAVIHALEKFTVYTLDIP
VLFGVSTTSPEETCAQVIREAKRTAPSIVYVPHIHVWWEIVGPTLKATFT
TLLQNIPSFAPVLLLATSDKPHSALPEEVQELFIRDYGEIFNVQLPDKEE
RTKFFEDLILKQAAKPPHERLKNLLKTVVKKSQNYNIFQLENLYAVISQC
IYRHRKDHDKTSLIQKMEQEVENFSCSR
3D structure
PDB8h3h Structure of the human ATAD2 AAA+ histone chaperone reveals mechanism of regulation and inter-subunit communication.
ChainE
Resolution3.15 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 3.6.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ATP E G429 G470 G472 K473 T474 L475 G636 A637 G8 G49 G51 K52 T53 L54 G215 A216
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity

View graph for
Molecular Function
External links
PDB RCSB:8h3h, PDBe:8h3h, PDBj:8h3h
PDBsum8h3h
PubMed37770645
UniProtQ6PL18|ATAD2_HUMAN ATPase family AAA domain-containing protein 2 (Gene Name=ATAD2)

[Back to BioLiP]