Structure of PDB 8gpn Chain E

Receptor sequence
>8gpnE (length=98) Species: 8355 (Xenopus laevis) [Search protein sequence]
KPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQS
SAVMALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGER
3D structure
PDB8gpn Menin "reads" H3K79me2 mark in a nucleosomal context.
ChainE
Resolution3.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna E R40 Y41 P43 V46 A47 R52 K64 P66 R69 R4 Y5 P7 V10 A11 R16 K28 P30 R33
BS02 dna E H39 R40 R42 T45 R72 F84 Q85 V117 T118 H3 R4 R6 T9 R36 F48 Q49 V81 T82
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome

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Molecular Function
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Cellular Component
External links
PDB RCSB:8gpn, PDBe:8gpn, PDBj:8gpn
PDBsum8gpn
PubMed36795828
UniProtP84233|H32_XENLA Histone H3.2

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