Structure of PDB 8gao Chain E

Receptor sequence
>8gaoE (length=432) Species: 2681598 (Escherichia phage T4) [Search protein sequence]
MVEIILSHLIFDQAYFSKVWPYMDSEYFESGPAKNTFKLIKSHVNEYHSV
PSINALNVALENSSFTETEYSGVKTLISKLADSPEDHSWLVKETEKYVQQ
RAMFNATSKIIEIQTNAELPPEKRNKKMPDVGAIPDIMRQALSISFDSYV
GHDWMDDYEARWLSYMNKARKVPFKLRILNKITKGGAETGTLNVLMAGVN
VGKSLGLCSLAADYLQLGHNVLYISMQMAEEVCAKRIDANMLDVSLDDID
DGHISYAEYKGKMEKWREKSTLGRLIVKQYPTGGADANTFRSLLNELKLK
KNFVPTIIIVDYLGICKSCRIRVYSENSYTTVKAIAEELRALAVETETVL
WTAAQVGKQAWDSSDVNMSDIAESAGLPATADFMLAVIETEELAAAEQQL
IKQIKSRYGDKNKWNKFLMGVQKGNQKWVEIE
3D structure
PDB8gao Structural basis of the T4 bacteriophage primosome assembly and primer synthesis.
ChainE
Resolution4.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.4.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna E N327 S328 Y329 K358 A372 N327 S328 Y329 K358 A372
BS02 AGS E V199 N200 G202 K203 S204 L205 R236 K423 V199 N200 G202 K203 S204 L205 R236 K423
BS03 AGS E R407 Y408 G409 D410 K411 R407 Y408 G409 D410 K411
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003678 DNA helicase activity
GO:0004386 helicase activity
GO:0005524 ATP binding
GO:0016787 hydrolase activity
GO:0017116 single-stranded DNA helicase activity
Biological Process
GO:0006260 DNA replication
GO:0006268 DNA unwinding involved in DNA replication
GO:0006269 DNA replication, synthesis of primer
GO:0032508 DNA duplex unwinding
GO:0039686 bidirectional double-stranded viral DNA replication
GO:0039693 viral DNA genome replication
Cellular Component
GO:0005829 cytosol
GO:1990077 primosome complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8gao, PDBe:8gao, PDBj:8gao
PDBsum8gao
PubMed37474605
UniProtP04530|HELIC_BPT4 DnaB-like replicative helicase (Gene Name=41)

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