Structure of PDB 8g7r Chain E

Receptor sequence

>8g7rE (length=201) Species: 562 (Escherichia coli)

MELVLKDAQSALTVSETTFGRDFNEALVHQVVVAYAAGARQGTRAQKTRA
EVTGSGKKPWRQKGTGRARSGSIKSPIWRSGGVTFAARPQDHSQKVNKKM
YRGALKSILSELVRQDRLIVVEKFSVEAPKTKLLAQKLKDMALEDVLIIT
GELDENLFLAARNLHKVDVRDATGIDPVSLIAFDKVVMTADAVKQVEEML
A

3D structure

• PDB: 8g7r Structures of the ribosome bound to EF-Tu-isoleucine tRNA elucidate the mechanism of AUG avoidance
• Chain: E
• Resolution: 2.8 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	E	H29 Q30 Y35 R40 Q41 T43 R44 Q46 R49 A50 S55 K57 Q62 K63 R67 A68 R69 G71 I77 R79 T84 F85 K95 N97 K98 K99 M100 Y101 R102 K130 T131 K132 L159 R162 N163 L164 H165 T173	H29 Q30 Y35 R40 Q41 T43 R44 Q46 R49 A50 S55 K57 Q62 K63 R67 A68 R69 G71 I77 R79 T84 F85 K95 N97 K98 K99 M100 Y101 R102 K130 T131 K132 L159 R162 N163 L164 H165 T173
BS02	MG	E	N97 K98 K99	N97 K98 K99

Gene Ontology

Molecular Function

• GO:0003735 structural constituent of ribosome
• GO:0019843 rRNA binding

Biological Process

• GO:0006412 translation

Cellular Component

• GO:0005840 ribosome
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:8g7r, PDBe:8g7r, PDBj:8g7r
• PDBsum: 8g7r
• PubMed: 38538914
• UniProt: A1AGK6|RL4_ECOK1 Large ribosomal subunit protein uL4 (Gene Name=rplD)