Structure of PDB 8g3p Chain E

Receptor sequence
>8g3pE (length=388) Species: 11320 (Influenza A virus) [Search protein sequence]
AEYRNWSKPQCGITGFAPFSKDNSIRLSAGGDIWVTREPYVSCDLDKCYQ
FALGQGTTLNNVHSNNTVRDRTPYRTLLMNELGVPFHLGTKQVCIAWSSS
SCHDGKAWLHVCITGDDKNATASFIYNGRLVDSVVSWSNDILRTQESECV
CINGTCTVVMTDGNATGKADTKILFIEEGKIVHTSKLSGSAQHVEECSCY
PRYPGVRCVCRDNWKGSNRPIIDINIKDHSIVSSYVCSGLVGDTPRKSDS
SSSSHCLNPNNEEGGHGVKGWAFDDGNDVWMGRTINETSRLGYETFKVVE
GWSNPKSKLQINRQVIVDRGDRSGYSGIFSVEGKSCINRCFYVELIRGRK
EETEVLWTSNSIVVFCGTSGTYGTGSWPDGADLNLMHT
3D structure
PDB8g3p A pan-influenza antibody inhibiting neuraminidase via receptor mimicry.
ChainE
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.2.1.18: exo-alpha-sialidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 BMA E Q391 I392 R394 Q310 I311 R313
BS02 MAN E Q391 R394 Q310 R313
BS03 CA E D293 G297 D324 G345 H347 D212 G216 D243 G264 H266
Gene Ontology
Molecular Function
GO:0004308 exo-alpha-sialidase activity
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0046761 viral budding from plasma membrane
Cellular Component
GO:0016020 membrane
GO:0033644 host cell membrane
GO:0055036 virion membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8g3p, PDBe:8g3p, PDBj:8g3p
PDBsum8g3p
PubMed37258672
UniProtA0A5P8ETS7

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