Structure of PDB 8fs5 Chain E

Receptor sequence
>8fs5E (length=353) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
SLWVDKYRPKSLNALSHNEELTNFLKSLSDQPRDLPHLLLYGPNGTGKKT
RCMALLESIFGPGVYRLKIDVRQFVTASNRKLELNVVSSPYHLEITPSDM
GNNDRIVIQELLKEVAQMEQVDFQDSKDGLAHRYKCVIINEANSLTKDAQ
AALRRTMEKYSKNIRLIMVCDSMSPIIAPIKSRCLLIRCPAPSDSEISTI
LSDVVTNERIQLETKDILKRIAQASNGNLRVSLLMLESMALNNELALKSS
SPIIKPDWIIVIHKLTRKIVKERSVNSLIECRAVLYDLLAHCIPANIILK
ELTFSLLDVETLNTTNKSSIIEYSSVFDERLSLGNKAIFHLEGFIAKVMC
CLD
3D structure
PDB8fs5 Structures of 9-1-1 DNA checkpoint clamp loading at gaps from start to finish and ramification to biology.
ChainE
Resolution2.76 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 AGS E R155 E159 R184 R154 E158 R183
BS02 ADP E V5 R9 P10 G46 T47 G48 K49 K50 T51 I201 L230 R231 V4 R8 P9 G45 T46 G47 K48 K49 T50 I200 L229 R230
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003689 DNA clamp loader activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
Biological Process
GO:0000077 DNA damage checkpoint signaling
GO:0006260 DNA replication
GO:0006261 DNA-templated DNA replication
GO:0006271 DNA strand elongation involved in DNA replication
GO:0006272 leading strand elongation
GO:0006281 DNA repair
GO:0007062 sister chromatid cohesion
GO:0007064 mitotic sister chromatid cohesion
GO:0090618 DNA clamp unloading
Cellular Component
GO:0005634 nucleus
GO:0005663 DNA replication factor C complex
GO:0031389 Rad17 RFC-like complex
GO:0031390 Ctf18 RFC-like complex
GO:0031391 Elg1 RFC-like complex

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Biological Process
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Cellular Component
External links
PDB RCSB:8fs5, PDBe:8fs5, PDBj:8fs5
PDBsum8fs5
PubMed37205533
UniProtP38251|RFC5_YEAST Replication factor C subunit 5 (Gene Name=RFC5)

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