Structure of PDB 8fjl Chain E

Receptor sequence
>8fjlE (length=1106) Species: 185783 (Golden shiner reovirus) [Search protein sequence]
VTPIVNPSSYVCNVCNARFSTMSALSEHLRSDHRDDASTLLATPMINNAI
RSFLTAWDGIRILSPDVSSKHLSAYLDSAVANGPELIVEDTGLCTSFMLL
DNIPSAHLTKELIGFTWFMQMYQMTPPLPEGAVNRIVCMTNWASLGDEGR
GLEVRLPPPTDSSVHAYKTVLSRGYIDNAQFNPLALRSNVLLMLLQFTLS
NLKINKSSTFTSDVTTITSGRMIRAFEGRPELLALAYPGRAVLPTQTKNA
QFLSTAIADRIGRLDRANLIGGEVSAMVECMELCDALTLHIRETYVMLLR
SMHQDPTQIVQIVNECANNLLNSTIPISLRPTILCPWFASSEDLRLQQVM
HLVNISSNTAAALPLVEALSTLLRSVTPLVLDPTVLTNAITTISESTTQT
ISPISEILRLLQPMGNDYAAFWKCIASWAYNGLVTTVLSEDAFPDSSQSI
THLPSMWKCLFLTLAGPMTSDPHSPVKVFMALANLLAQPEPIAIGVPGMH
QTTPASQFSHPGVWPPGFLNPQLINPQQAPLLRAFAEHIRANWPQPSEFG
YGSTLQGSANLFIPPNRMVYPWPNQPLPRLTVAPTYDSAMSNWISTTIAF
FIRVVNSVNMTATVNDLTRRTMTGVMTAMRQVKTMTPFYIQHMCPTELSV
LASVTVTPPFQVPFTRLVQNDVITNVLVARVDPAQRGDAAVDIRATHATF
AAALPVDPAAIVVAMLCGQTETNLIPSHHYGKAFAPLFASNAMFTRNQRA
VITREAFVCARSAVAQCQDAGFLVPRPLDALRQFDVTSAAAAEIMHAVND
AFKTAFDLDGALLDGLALYGDPRIADLSAAYLQYGGNVVREHVPPGPSHI
HRTLQQVESTFMAEMNLFNVARGNLYLVQTATNGNWSPMAPVAAPPFVRG
GPNVRVVGRFGTIVPRPDGLEPQLIDDGNVPRDIAGDWVYPSDVLQVSVA
VFCDYVWPMVKAGRTRVLVELGHYVYTLHYYDPQISLDEAPILEEWLSKI
NPAGIPPVPFCIPIPQVYPCITARRVHYAFTSENNNDSLFSTNAASIDTA
FGENAAVSPLRWPGLVDPNYRVGTNDLPNRITLYNSLYRYNFTYPTLDGI
MYVRSA
3D structure
PDB8fjl Asymmetric reconstruction of the aquareovirus core at near-atomic resolution and mechanism of transcription initiation.
ChainE
Resolution3.27 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.4.13: RNA helicase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN E C119 C122 H135 H140 C12 C15 H28 H33
Gene Ontology
Molecular Function
GO:0003724 RNA helicase activity
GO:0004386 helicase activity
GO:0005524 ATP binding
GO:0016787 hydrolase activity
GO:0016887 ATP hydrolysis activity
GO:0046872 metal ion binding
Biological Process
GO:0006370 7-methylguanosine mRNA capping
Cellular Component
GO:0039616 T=2 icosahedral viral capsid
GO:0039625 viral inner capsid

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8fjl, PDBe:8fjl, PDBj:8fjl
PDBsum8fjl
PubMed36856784
UniProtQ8JU60|CAPSD_AQRVC Major inner capsid protein VP3 (Gene Name=S3)

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