Structure of PDB 8fja Chain E

Receptor sequence

>8fjaE (length=214) Species: 9606 (Homo sapiens) [Search protein sequence]

EVQLVESGGGLVQPGRSLRLSCAASGFTFDDYAMHWVRQAPGKGLEWVSG
ISWNSGSIAYADSVKGRFTISRDNAKNSLYLQMNSLRSEDTALYHCAKDW
RRTNYYGMDVWGQGTTVTVSSASTKGPSVFPLAPCTAALGCLVKDYFPEP
VTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTKTYTCNVD
HKPSNTKVDKRVES

3D structure

PDB

8fja CryoEM structure of REGN6972 Fab in complex with HLA-A2 MAGEA4 (230-239)

Chain

Resolution

3.0 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	E	R101 R102 Y106	R101 R102 Y106

External links

PDB	RCSB:8fja, PDBe:8fja, PDBj:8fja
PDBsum	8fja
PubMed

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