Structure of PDB 8fad Chain E

Receptor sequence
>8fadE (length=466) Species: 11676 (Human immunodeficiency virus 1) [Search protein sequence]
KLWVTVYYGVPVWKEATTTLFCASDAKAYDTEVHNVWATHACVPTDPNPQ
EVVLENVTENFNMWKNNMVEQMHEDIISLWDQSLKPCVKLTPLCVTLNCT
DLRNVTNISEGMRGEIKNCSFNITTSIRDKVKKDYALFYRLDVVPIDNDN
TSYRLINCNTSTITQACPKVSFEPIPIHYCTPAGFAILKCKDKKFNGTGP
CKNVSTVQCTHGIRPVVSTQLLLNGSLAEEEVVIRSSNFTDNAKNIIVQL
KESVEINCTRPNNNTRKSIHIGPGRAFYTTGDIIGDIRQAHCNISRTKWN
NTLNQIATKLKEQFGNNKTIVFNQSSGGDPEIVMHSFNCGGEFFYCNSTQ
LFNSTWNFNGTWNLTQSNGTEGNDTITLPCRIKQIINMWQEVGKAMYAPP
IRGQIRCSSNITGLILTRDGGNNHNNDTETFRPGGGDMRDNWRSELYKYK
VVKIEPLGVAPTKAKR
3D structure
PDB8fad Asymmetric conformations of cleaved HIV-1 envelope glycoprotein trimers in styrene-maleic acid lipid nanoparticles.
ChainE
Resolution4.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 83G E I109 D113 V255 F382 M426 W427 K432 I77 D81 V217 F343 M388 W389 K394
Gene Ontology
Cellular Component
GO:0016020 membrane
GO:0019031 viral envelope

View graph for
Cellular Component
External links
PDB RCSB:8fad, PDBe:8fad, PDBj:8fad
PDBsum8fad
PubMed37202420
UniProtB0FDK7

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