Structure of PDB 8f7z Chain E

Receptor sequence

>8f7zE (length=213) Species: 9606 (Homo sapiens) [Search protein sequence]

KVLVQSGAEVKKPGASVKVSCRAFGYTFTGNPLHWVRQAPGQGLEWLGWI
NPHSGDTFTSQKFQGRVYMTRDKSINTAFLDVTRLTSDDTGIYYCARDKY
YGNEAVGMDVWGQGTSVTVSSASTKGPSVFPLAPTAALGCLVKDYFPEPV
TVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNH
KPSNTKVDKKVEP

3D structure

PDB

8f7z Structural mechanism for broad HIV-1 fusion peptide neutralization revealed by directed antibody evolution

Chain

Resolution

2.7 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	E	N32 P33 W50 N52 Y97 N100 E100A A100B	N31 P32 W49 N51 Y100 N103 E104 A105

External links

PDB	RCSB:8f7z, PDBe:8f7z, PDBj:8f7z
PDBsum	8f7z
PubMed	37989731

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