Structure of PDB 8f2k Chain E

Receptor sequence
>8f2kE (length=469) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
PITGKVTAVIGAIVDVHFEQSELPAILNALEIKTPQGKLVLEVAQHLGEN
TVRTIAMDGTEGLVRGEKVLDTGGPISVPVGRETLGRIINVIGEPIDERG
PIKSKLRKPIHADPPSFAEQSTSAEILETGIKVVDLLAPYARGGKIGLFG
GAGVGKTVFIQELINNIAKAHGGFSVFTGVGERTREGNDLYREMKETGVI
NLEGESKVALVFGQMNEPPGARARVALTGLTIAEYFRDEEGQDVLLFIDN
IFRFTQAGSEVSALLGRIPSAVGYQPTLATDMGLLQERITTTKKGSVTSV
QAVYVPADDLTDPAPATTFAHLDATTVLSRGISELGIYPAVDPLDSKSRL
LDAAVVGQEHYDVASKVQETLQTYKSLQDIIAILGMDELSEQDKLTVERA
RKIQRFLSQPFAVAEVFTGIPGKLVRLKDTVASFKAVLEGKYDNIPEHAF
YMVGGIEDVVAKAEKLAAE
3D structure
PDB8f2k Late-stage diversification of cruentaren A based on cryo-EM structure with ATP synthase
ChainE
Resolution2.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 7.1.2.2: H(+)-transporting two-sector ATPase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ATP E G160 G162 K163 T164 V165 R190 Y345 F418 A421 F424 G153 G155 K156 T157 V158 R183 Y338 F411 A414 F417
BS02 XBC E E341 G343 Y345 F424 T425 I427 Y458 E334 G336 Y338 F417 T418 I420 Y451
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
GO:0046933 proton-transporting ATP synthase activity, rotational mechanism
GO:0046961 proton-transporting ATPase activity, rotational mechanism
Biological Process
GO:0006754 ATP biosynthetic process
GO:0015986 proton motive force-driven ATP synthesis
GO:0042776 proton motive force-driven mitochondrial ATP synthesis
GO:0046034 ATP metabolic process
GO:1902600 proton transmembrane transport
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005758 mitochondrial intermembrane space
GO:0005829 cytosol
GO:0016020 membrane
GO:0045259 proton-transporting ATP synthase complex
GO:0045261 proton-transporting ATP synthase complex, catalytic core F(1)
GO:0045267 proton-transporting ATP synthase, catalytic core

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8f2k, PDBe:8f2k, PDBj:8f2k
PDBsum8f2k
PubMed36867738
UniProtP00830|ATPB_YEAST ATP synthase subunit beta, mitochondrial (Gene Name=ATP2)

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