Structure of PDB 8ek5 Chain E

Receptor sequence

>8ek5E (length=227) Species: 9606 (Homo sapiens) [Search protein sequence]

VLTQPPSVSVSPGQTASITCSGDSLGNKYACWYQQKPGQSPVLVIYQDSK
RPSGIPERFSGSNSGNTATLTISGTQAMDEADYYCQAWDSSRGYTVVFGT
GTKVTVSSEVQLLESGGGLVQPGGSLRLSCAASGFTFDSYAMSWVRQAPG
KGLEWVSAISGYGGSTYYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTA
VYYCAKYTYFLDAFDIWGQGTMVTVSS

3D structure

PDB

8ek5 Structural principles of peptide-centric Chimeric Antigen Receptor recognition guide therapeutic expansion.

Chain

Resolution

2.11 Å

3D
structure

[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	E	K140 W200 S202 R204 Y294 Y341 D344	K28 W88 S90 R92 Y162 Y209 D212

External links

PDB	RCSB:8ek5, PDBe:8ek5, PDBj:8ek5
PDBsum	8ek5
PubMed	38039376

[Back to BioLiP]