Structure of PDB 8eho Chain E

Receptor sequence
>8ehoE (length=166) Species: 28344 (Porcine reproductive and respiratory syndrome virus) [Search protein sequence]
VPTCGITTYSPPTDGSCGWHVLAAIMNRMINGDFTSPLTQYNRPEDDWAS
DYDLVQAIQCLQLPATVVRNRACPNAKYLIKLNGVHWEVEVRSGMAPRSL
PRECVVGVCSEGCVAPPYPADGLPKRALEALASAYRLPSDCVSSGIADFL
ANPPPQEFWTLDKMLT
3D structure
PDB8eho Demonstrating the importance of porcine reproductive and respiratory syndrome virus papain-like protease 2 deubiquitinating activity in viral replication by structure-guided mutagenesis
ChainE
Resolution2.85 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.19.12: ubiquitinyl hydrolase 1.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN E C485 C516 C521 C525 C73 C104 C109 C113
BS02 3CN E G427 C429 W460 V497 G15 C17 W48 V85
Gene Ontology
Biological Process
GO:0016032 viral process
GO:0019082 viral protein processing

View graph for
Biological Process
External links
PDB RCSB:8eho, PDBe:8eho, PDBj:8eho
PDBsum8eho
PubMed38096325
UniProtW0NX70

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