Structure of PDB 8edg Chain E

Receptor sequence
>8edgE (length=550) Species: 7370 (Musca domestica) [Search protein sequence]
MDNLEVKAKINQGLYKITPRHKGTSFIWNVLADIQKEDDTLVEGWVFCRK
CEKVLKYTTRQTSNLCRHKCCASLKQSRELKTVSADCKKEAIEKCAQWVV
RDCRPFSAVSGSGFIDMIKFFIKVGAEYGEHVNVEELLPSPITLSRKVTS
DAKEKKALISREIKSAVEKDGASATIDLWTDNYIKRNFLGVTLHYHENNE
LRDLILGLKSLDFERSTAENIYKKLKAIFSQFNVEDLSSIKFVTDRGANV
VKSLANNIRINCSSHLLSNVLENSFEETPELNMPILACKNIVKYFKKANL
QHRLRSSLKSECPTRWNSTYTMLRSILDNWESVIQILSEAGETQRIVHIN
KSIIQTMVNILDGFERIFKELQTCSSPSLCFVVPSILKVKEICSPDVGDV
ADIAKLKVNIIKNVRIIWEENLSIWHYTAFFFYPPALHMQQEKVAQIKEF
CLSKMEDPVCPSDEFEFYRKEIVILSEDFKVMEWWNLNSKKYPKLSKLAL
SLLSIPASSAASERTFSLAGNIITEKRNRIGQQTVDSLLFLNSFYKNFCK
3D structure
PDB8edg Zinc-finger BED domains drive the formation of the active Hermes transpososome by asymmetric DNA binding.
ChainE
Resolution4.64 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna E K56 K59 Q64 N67 K91 S310 R318 K53 K56 Q61 N64 K88 S307 R315
BS02 dna E S28 R63 Q64 T65 S66 R70 P108 F109 S110 K372 R573 S25 R60 Q61 T62 S63 R67 P105 F106 S107 K369 R514
BS03 dna E K585 R586 I589 K526 R527 I530
BS04 dna E N587 R588 N528 R529
BS05 ZN E C51 C54 H71 C73 C48 C51 H68 C70
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0046872 metal ion binding
GO:0046983 protein dimerization activity
Biological Process
GO:0006357 regulation of transcription by RNA polymerase II
Cellular Component
GO:0005634 nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8edg, PDBe:8edg, PDBj:8edg
PDBsum8edg
PubMed37491363
UniProtQ25438

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