Structure of PDB 8dr5 Chain E

Receptor sequence
>8dr5E (length=352) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
SLWVDKYRPKSLNALSHNEELTNFLKSLSDQPRDLPHLLLYGPNGTGKKT
RCMALLESIFGPGVYRLKIDVRQFVTASNRKLELNVVSSPYHLEITPSDM
GNNDRIVIQELLKEVAQMEQVDFQDSKDGLAHRYKCVIINEANSLTKDAQ
AALRRTMEKYSKNIRLIMVCDSMSPIIAPIKSRCLLIRCPAPSDSEISTI
LSDVVTNERIQLETKDILKRIAQASNGNLRVSLLMLESMALNNELALKSS
SPIIKPDWIIVIHKLTRKIVKERSVNSLIECRAVLYDLLAHCIPANIILK
ELTFSLLDVETLNTTNKSSIIEYSSVFDERLSLGNKAIFHLEGFIAKVMC
CL
3D structure
PDB8dr5 Multistep loading of a DNA sliding clamp onto DNA by replication factor C.
ChainE
Resolution2.76 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna E N336 K337 N335 K336
BS02 AGS E R155 E159 R184 R154 E158 R183
BS03 GDP E V5 R9 P10 S17 H18 G46 G48 K49 K50 T51 R52 I201 L230 R231 V4 R8 P9 S16 H17 G45 G47 K48 K49 T50 R51 I200 L229 R230
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003689 DNA clamp loader activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
Biological Process
GO:0000077 DNA damage checkpoint signaling
GO:0006260 DNA replication
GO:0006261 DNA-templated DNA replication
GO:0006271 DNA strand elongation involved in DNA replication
GO:0006272 leading strand elongation
GO:0006281 DNA repair
GO:0007062 sister chromatid cohesion
GO:0007064 mitotic sister chromatid cohesion
GO:0090618 DNA clamp unloading
Cellular Component
GO:0005634 nucleus
GO:0005663 DNA replication factor C complex
GO:0031389 Rad17 RFC-like complex
GO:0031390 Ctf18 RFC-like complex
GO:0031391 Elg1 RFC-like complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8dr5, PDBe:8dr5, PDBj:8dr5
PDBsum8dr5
PubMed35939393
UniProtP38251|RFC5_YEAST Replication factor C subunit 5 (Gene Name=RFC5)

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