Structure of PDB 8dr1 Chain E

Receptor sequence
>8dr1E (length=354) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
MSLWVDKYRPKSLNALSHNEELTNFLKSLSDQPRDLPHLLLYGPNGTGKK
TRCMALLESIFGPGVYRLKIDVRQFVTASNRKLELNVVSSPYHLEITPSD
MGNNDRIVIQELLKEVAQMEQVDFQDSKDGLAHRYKCVIINEANSLTKDA
QAALRRTMEKYSKNIRLIMVCDSMSPIIAPIKSRCLLIRCPAPSDSEIST
ILSDVVTNERIQLETKDILKRIAQASNGNLRVSLLMLESMALNNELALKS
SSPIIKPDWIIVIHKLTRKIVKERSVNSLIECRAVLYDLLAHCIPANIIL
KELTFSLLDVETLNTTNKSSIIEYSSVFDERLSLGNKAIFHLEGFIAKVM
CCLD
3D structure
PDB8dr1 Multistep loading of a DNA sliding clamp onto DNA by replication factor C.
ChainE
Resolution2.14 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna E N103 K337 N103 K337
BS02 AGS E R155 R184 R155 R184
BS03 GDP E V5 P10 L16 S17 H18 G46 T47 G48 K49 K50 T51 R52 L230 R231 V5 P10 L16 S17 H18 G46 T47 G48 K49 K50 T51 R52 L230 R231
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003689 DNA clamp loader activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
Biological Process
GO:0000077 DNA damage checkpoint signaling
GO:0006260 DNA replication
GO:0006261 DNA-templated DNA replication
GO:0006271 DNA strand elongation involved in DNA replication
GO:0006272 leading strand elongation
GO:0006281 DNA repair
GO:0007062 sister chromatid cohesion
GO:0007064 mitotic sister chromatid cohesion
GO:0090618 DNA clamp unloading
Cellular Component
GO:0005634 nucleus
GO:0005663 DNA replication factor C complex
GO:0031389 Rad17 RFC-like complex
GO:0031390 Ctf18 RFC-like complex
GO:0031391 Elg1 RFC-like complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8dr1, PDBe:8dr1, PDBj:8dr1
PDBsum8dr1
PubMed35939393
UniProtP38251|RFC5_YEAST Replication factor C subunit 5 (Gene Name=RFC5)

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