Structure of PDB 8ct0 Chain E

Receptor sequence
>8ct0E (length=168) Species: 1894 (Kitasatospora aureofaciens) [Search protein sequence]
EPLSLPLDLAPGLVDGDTFLSIMGALPTGVTVVTTLGPDGEPYGLTCSAA
CSVSKAPPLLLVCINRDSRVLKALLERGEFAVNVLRGGGESTSARFAAPV
DDRFRDVRWEPGSAGGVPVMSADVVAHAECRVAAALDAGDHTIVIGAVVA
GGPRPSPLMYWRRSYARW
3D structure
PDB8ct0 Crystal structures and complex formation of halogenase CtcP and FAD reductase CtcQ from the chlortetracycline biosynthetic pathway
ChainE
Resolution2.45 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.5.1.36: flavin reductase (NADH).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FAD E L23 N68 H144 Y166 R169 L20 N65 H141 Y160 R163
BS02 FAD E T49 C50 S51 A52 C66 I67 S71 R72 A100 R106 T46 C47 S48 A49 C63 I64 S68 R69 A97 R103
Gene Ontology
Molecular Function
GO:0010181 FMN binding
GO:0016491 oxidoreductase activity
GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor
GO:0036382 flavin reductase (NADH) activity
GO:0042602 riboflavin reductase (NADPH) activity

View graph for
Molecular Function
External links
PDB RCSB:8ct0, PDBe:8ct0, PDBj:8ct0
PDBsum8ct0
PubMed
UniProtS4S3E3|CTCQ_KITAU Flavin reductase (NADH) (Gene Name=ctcQ)

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