Structure of PDB 8cso Chain E

Receptor sequence
>8csoE (length=231) Species: 1125630 (Klebsiella pneumoniae subsp. pneumoniae HS11286) [Search protein sequence]
HHHMVVALDYDNRDKALAFVDRIDPRDCRLKVGKEMFTLLGPQFVRDLHQ
RGFEVFLDLKFHDIPNTTARAVAAAAELGVWMVNVHASGGARMMTAAREA
LLPFGKDAPLLIAVTVLTSMESSDLQDLGITLSPADYAAKLAALTQRCGL
DGVVCSAQEAVRFKHELGQAFKLVTPGIRPQGSDAGDQRRIMTPEQAQEA
GVDYMVIGRPVTQSADPAATLRAINDSLRKG
3D structure
PDB8cso Crystal Structure of Orotidine 5'-phosphate decarboxylase from Klebsiella pneumoniae in complex with Guanosine-5'-monophosphate
ChainE
Resolution2.6 Å
3D
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Enzymatic activity
Enzyme Commision number 4.1.1.23: orotidine-5'-phosphate decarboxylase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 U5P E D5 K27 K56 T114 P172 R175 G204 R205 D9 K31 K60 T118 P176 R179 G208 R209
Gene Ontology
Molecular Function
GO:0004590 orotidine-5'-phosphate decarboxylase activity
GO:0016831 carboxy-lyase activity
Biological Process
GO:0006207 'de novo' pyrimidine nucleobase biosynthetic process
GO:0006221 pyrimidine nucleotide biosynthetic process
GO:0044205 'de novo' UMP biosynthetic process
Cellular Component
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8cso, PDBe:8cso, PDBj:8cso
PDBsum8cso
PubMed
UniProtA0A0H3GNE4

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