Structure of PDB 8cap Chain E

Receptor sequence
>8capE (length=242) Species: 142864 (Cylindrospermum stagnale) [Search protein sequence]
EPTFVVNASLLPSKVLGLQVQRPQSFNYQPGDYLFIKCPGISKFEWHPFT
ISSAPEMPDVLTLHIRAVGSWTGKLYQLIREQREEWIRSGPGVPVYIDGP
YGTPSTHIFESKYAILICAGIGVTPFASILKSILHRNQQNPAKMPLKKVH
FYWLNREQKAFEWFVELLSKIEAEDTNNLFDLNLYLTSRTKTGRPDWEEI
FKDVAKQHAPDNVEVFFCGPTGLALQLRHLCTKYGFGYRKEN
3D structure
PDB8cap Targeting ROS through the discovery of isoform-selective NADPH oxidase inhibitors
ChainE
Resolution3.0 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FAD E T671 R678 T221 R228
BS02 FAD E Y445 H459 P460 F461 T462 H476 G481 W483 T484 T541 Y33 H47 P48 F49 T50 H64 G69 W71 T72 T124
BS03 U4O E V427 I538 T541 F578 V15 I121 T124 F161
Gene Ontology
Molecular Function
GO:0016491 oxidoreductase activity
Cellular Component
GO:0016020 membrane

View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:8cap, PDBe:8cap, PDBj:8cap
PDBsum8cap
PubMed37884805
UniProtK9WT99

[Back to BioLiP]