Structure of PDB 8c82 Chain E

Receptor sequence
>8c82E (length=183) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
TTEPVKDHRRRRAAAIISHVEPETFEDENDQQLLPNMNATWVDQRGAWII
HVVIIILLKLFYNLFPGVTTEWSWTLTNMTYVIGSYVMFHLIKGTPFDFN
GGAYDNLTMWEQIDDETLYTPSRKFLISVPIALFLVSTHYAHYDLKLFSW
NCFLTTFGAVVPKLPVTHRLRISIPGITGRAQI
3D structure
PDB8c82 Structure of the ceramide-bound SPOTS complex.
ChainE
Resolution3.4 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 Z8A E N76 W79 Y100 T118 P134 N38 W41 Y62 T80 P96
BS02 Q7G E I130 Q220 I92 Q182
Gene Ontology
Molecular Function
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0006672 ceramide metabolic process
GO:0006986 response to unfolded protein
GO:0030148 sphingolipid biosynthetic process
GO:0090155 negative regulation of sphingolipid biosynthetic process
GO:0090156 intracellular sphingolipid homeostasis
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0016020 membrane
GO:0017059 serine palmitoyltransferase complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8c82, PDBe:8c82, PDBj:8c82
PDBsum8c82
PubMed37794019
UniProtP53224|ORM1_YEAST Protein ORM1 (Gene Name=ORM1)

[Back to BioLiP]