Structure of PDB 7z1z Chain E

Receptor sequence
>7z1zE (length=260) Species: 36374 (Visna/maedi virus EV1 KV1772) [Search protein sequence]
WIENIPLAEEEHNKWHQDAVSLHLEFGIPRTAAEDIVQQCDVCQENKIDH
WQVDYTHYEDKIILVWVETNSGLIYAERVKGETGQEFRVQTMKWYAMFAP
KSLQSDNGPAFVAESTQLLMKYLGIEHTTGIPWNPQSQALVERTHQTLKN
TLEKLIPMFNAFESALAGTLITLNIKRKGGLGTSPMDIFIFNKEQQRIQQ
QSKSKQEKIRFCYYRTRKRGHPGEWQGPTQVLWGGDGAIVVKDRGTDRYL
VIANKDVKFI
3D structure
PDB7z1z Multivalent interactions essential for lentiviral integrase function.
ChainE
Resolution3.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.-
2.7.7.49: RNA-directed DNA polymerase.
2.7.7.7: DNA-directed DNA polymerase.
3.1.-.-
3.1.13.2: exoribonuclease H.
3.1.26.4: ribonuclease H.
3.4.23.-
3.6.1.23: dUTP diphosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN E H12 H16 C40 C43 H12 H16 C40 C43
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0008270 zinc ion binding
Biological Process
GO:0015074 DNA integration

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Molecular Function
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Biological Process
External links
PDB RCSB:7z1z, PDBe:7z1z, PDBj:7z1z
PDBsum7z1z
PubMed
UniProtP35956|POL_VILVK Gag-Pol polyprotein (Gene Name=pol)

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