Structure of PDB 7yqk Chain E

Receptor sequence
>7yqkE (length=99) Species: 9606 (Homo sapiens) [Search protein sequence]
KKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQ
SSAVMALQEACEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGER
3D structure
PDB7yqk Chemical Synthesis of Post-Translationally Modified H2AX Reveals Redundancy in Interplay between Histone Phosphorylation, Ubiquitination, and Methylation on the Binding of 53BP1 with Nucleosomes.
ChainE
Resolution3.38 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna E R40 Y41 G44 V46 R49 R63 K64 L65 P66 R69 R83 R5 Y6 G9 V11 R14 R28 K29 L30 P31 R34 R48
BS02 dna E R42 R63 R72 R83 F84 Q85 R116 V117 T118 R7 R28 R37 R48 F49 Q50 R81 V82 T83
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome

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Molecular Function

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Cellular Component
External links
PDB RCSB:7yqk, PDBe:7yqk, PDBj:7yqk
PDBsum7yqk
PubMed36166692
UniProtP68431|H31_HUMAN Histone H3.1 (Gene Name=H3C1)

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