Structure of PDB 7yo1 Chain E

Receptor sequence
>7yo1E (length=879) Species: 9606 (Homo sapiens) [Search protein sequence]
PCDSRGQRMWWAFLASSMVTFFGGLFIILLWRTLKYLWTWMTSVKDWAGV
MISAQTLTGRVLVVLVFALSIGALVIYFIDSSNPIESCQNFYKDFTLQID
MAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSW
LGLRFLRALRLIQFSEILQFLNILKTSNSIKLVNLLSIFISTWLTAAGFI
HLVENSGDPWENFQNNQALTYWECVYLLMVTMSTVGYGDVYAKTTLGRLF
MVFFILGGLAMFASYVPEIIELIGNRKKYGGSYSAVSGRKHIVVCGHITL
ESVSNFLKAFLHKARDDVNVEIVFLHNISPNLELEALFKRHFTQVEFYQG
SVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRVISIKNYHPK
IRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGL
STMLANLFSMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSAFVGLSFPTV
CELCFVKLKLLMISRILINPGNGTLGFFIASDAKEVKRAFFYCKKYDSTG
MFHWCAPKEIEKVILTRSEAAMTVLSGHVVVCIFGDVSSALIGLRNLVMP
LRASNFHYHELKHIVFVGSIEYLKREWETLHNFPKVSILPGTPLSRADLR
AVNINLCDMCVILSANQNNIDDTSLQDKECILASLNIKSMQFDTTGVNIP
IITELVNDTNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSAT
YFNDNILTLIRTLVTGGATPELEALIAEENALRGGYSTPQTLANRDRCRV
AQLALLDGPFADLGDGGCYGDLFCKALKTYNMLCFGIYRLRDAHLSTPSQ
CTKRYVITNPPYEFELVPTDLIFCLMQFD
3D structure
PDB7yo1 Structural basis for dual allosteric gating modulation of Slo1-LRRC channel complex
ChainE
Resolution3.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA E R514 S533 E535 S600 R461 S480 E482 S531
BS02 CA E Q889 D892 D895 D897 Q712 D715 D718 D720
Gene Ontology
Molecular Function
GO:0005216 monoatomic ion channel activity
Biological Process
GO:0006811 monoatomic ion transport
GO:0006813 potassium ion transport
GO:0055085 transmembrane transport
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7yo1, PDBe:7yo1, PDBj:7yo1
PDBsum7yo1
PubMed
UniProtQ12791|KCMA1_HUMAN Calcium-activated potassium channel subunit alpha-1 (Gene Name=KCNMA1)

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