Structure of PDB 7xk4 Chain E

Receptor sequence
>7xk4E (length=198) Species: 345073 (Vibrio cholerae O395) [Search protein sequence]
MEHYISLLVKSIFIENMALSFFLGMCTFLAVSKKVKTSFGLGIAVIVVLT
ISVPVNNLVYNLVLKPDALVEGVDLSFLNFITFIGVIAALVQILEMILDR
FFPPLYNALGIFLPLITVNCAIFGGVSFMVQRDYSFAESVVYGFGSGVGW
MLAIVALAGIREKMKYSDVPPGLRGLGITFITAGLMALGFMSFSGVQL
3D structure
PDB7xk4 Cryo-EM structures of Na + -pumping NADH-ubiquinone oxidoreductase from Vibrio cholerae.
ChainE
Resolution3.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 7.2.1.1: NADH:ubiquinone reductase (Na(+)-transporting).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FES E G24 C26 C120 G24 C26 C120
BS02 CA E S11 R132 Y142 S11 R132 Y142
Gene Ontology
Molecular Function
GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor
Biological Process
GO:0006814 sodium ion transport
GO:0022904 respiratory electron transport chain
Cellular Component
GO:0005886 plasma membrane
GO:0009276 Gram-negative-bacterium-type cell wall
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7xk4, PDBe:7xk4, PDBj:7xk4
PDBsum7xk4
PubMed35882843
UniProtA5F5Y5|NQRE_VIBC3 Na(+)-translocating NADH-quinone reductase subunit E (Gene Name=nqrE)

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