Structure of PDB 7xd0 Chain E

Receptor sequence
>7xd0E (length=98) Species: 9606 (Homo sapiens) [Search protein sequence]
KPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQS
SAVMALQEASEAYLVALFEDTNLCAIHAKRVTIMPKDIQLARRIRGER
3D structure
PDB7xd0 H2B Lys34 Ubiquitination Induces Nucleosome Distortion to Stimulate Dot1L Activity.
ChainE
Resolution3.48 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna E K37 R42 T45 R72 R83 V117 T118 M120 K1 R6 T9 R36 R47 V81 T82 M84
BS02 dna E R40 Y41 V46 R49 R63 L65 P66 R69 R4 Y5 V10 R13 R27 L29 P30 R33
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome

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Molecular Function
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Cellular Component
External links
PDB RCSB:7xd0, PDBe:7xd0, PDBj:7xd0
PDBsum7xd0
PubMed35739357
UniProtQ71DI3|H32_HUMAN Histone H3.2 (Gene Name=H3C15)

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