Structure of PDB 7xcn Chain E

Receptor sequence
>7xcnE (length=494) Species: 1434108 (Methanosarcina barkeri MS) [Search protein sequence]
AKNNAVAGFNALNGVELNLFTTDELKAIHYATMEVLMDPGIQVSDPEARQ
IFKENGCEVNEKTNVVKIPEYLVRKALQLAPSRFVLWGRDKKFNTVQECG
GKVHWTCFGTGVKVCKYQDGKYVTVDSVEKDIADIAKLCDWAENIDYFSL
PVSARDIAGQGAQDVHETLTPLANTAKHFHHIDPVGENVEYYRDIVKAYY
GGDEEEARKKPIFSMLLCPTSPLELSVNACQVIIKGARFGIPVNVLSMAM
SGGSSPVYLAGTLVTHNAEVLSGIVLAQLTVPGAKVWYGSSTTTFDLKKG
TAPVGSPELGLISAAVAKLAQFYGLPSYVAGSKSDAKVPDDQAGHEKTMT
TLLPALAGANTIYGAGMLELGMTFSMEQLVIDNDIFSMVKKAMQGIPVSE
ETLAVESIQKVGIGNNFLALKQTRQLVDYPSNPMLLDRHMFGDWAAAGSK
DLATVAHEKVEDVLKNHQVTPIDADIFKDMQAIVDKADKAFRGM
3D structure
PDB7xcn Insights into pyrrolysine function from structures of a trimethylamine methyltransferase and its corrinoid protein complex.
ChainE
Resolution2.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.1.1.250: [trimethylamine--corrinoid protein] Co-methyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 HCB E T111 V113 C219 T221 M249 M251 O334 G372 T110 V112 C218 T220 M248 M250 O333 G371
Gene Ontology
Molecular Function
GO:0008168 methyltransferase activity
GO:0043834 trimethylamine methyltransferase activity
Biological Process
GO:0015948 methanogenesis
GO:0032259 methylation

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:7xcn, PDBe:7xcn, PDBj:7xcn
PDBsum7xcn
PubMed36646841
UniProtO93658|MTTB_METBA Trimethylamine methyltransferase MttB (Gene Name=mttB)

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