Structure of PDB 7xa7 Chain E

Receptor sequence
>7xa7E (length=596) Species: 59477 (Rhinolophus affinis) [Search protein sequence]
STTEDRAKIFLDNFNREAEELSYQSSLASWEYNTNISDENVQKMDEAGAK
WSAFYEEQSKLAKNYPLEEIQTVPVKLQLQILQQSGSPVLSEDKSKRLNS
ILNAMSTIYSTGKVCKPNNPQECFLLEPGLDNIMGTSKDYNERLWAWEGW
RAEVGKQLRPLYEEYVVLKNEMARGYHYEDYGDYWRRDYETEESSGSGYS
RDQLMKDVDRIFTEIKPLYEHLHAYVRTKLMDTYPFHISPTGCLPAHLLG
DMWGRFWTNLYPLTVPFGQKPNIDVTDAMVNQGWDANRIFKEAEKFFVSV
GLPNMTEGFWNNSMLTEPGDGRKVVCHPTAWDLGKGDFRIKMCTKVTMED
FLTAHHEMGHIQYDMAYATQPYLLRNGANEGFHEAVGEVMSLSVATPKHL
KTMGLLSPDFLEDNETEINFLLKQALNIVGTLPFTYMLEKWRWMVFRGEI
PKEEWMKKWWEMKRDLVGVVEPVPHDETYCDPASLFHVANDYSFIRYYTR
TIFEFQFHEALCRIAQHDGPLHKCDISNSTDAGKKLHQMLSVGKSQPWTV
TLKDIVDSRNMDVGPLLRYFEPLYTWLQEQNRKSYVGWNTDWSPYS
3D structure
PDB7xa7 Structural basis of SARS-CoV-2 and its variants binding to intermediate horseshoe bat ACE2.
ChainE
Resolution3.31 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.-.-
3.4.17.23: angiotensin-converting enzyme 2.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN E H357 H361 E385 H356 H360 E384
Gene Ontology
Molecular Function
GO:0008237 metallopeptidase activity
GO:0008241 peptidyl-dipeptidase activity
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7xa7, PDBe:7xa7, PDBj:7xa7
PDBsum7xa7
PubMed35874946
UniProtA0A7D7FA76

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