Structure of PDB 7x52 Chain E

Receptor sequence
>7x52E (length=458) Species: 226186 (Bacteroides thetaiotaomicron VPI-5482) [Search protein sequence]
EDLNFRKGDAKTDVFGSDRMLQPSPVERIPDGPTTPEVAYQMVKDETFAQ
TQPRLNLATFVTTYMDDYATKLMNEAININYIDETEYPRIAVMNGKCINI
VANLWNSPEKDTWKTGALAIGSSEACMLGGVAAWLRWRKKRQAQGKPFDK
PNFVISTGFQVVWEKFAQLWQIEMREVPLTLEKTTLDPEEALKMCDENTI
CVVPIQGVTWTGLNDDVEALDKALDAYNAKTGYDIPIHVDAASGGFILPF
LYPDTKWDFRLKWVLSISVSGHKFGLVYPGLGWVCWKGKEYLPEEMSFSV
NYLGANITQVGLNFSRPAAQILGQYYQFIRLGFQGYKEVQYNSLQIAKYI
HGEIAKMAPFVNYSENVVNPLFIWYLKPEYAKSAKWTLYDLQDKLSQHGW
MVPAYTLPSKLEDYVVMRVVVRQGFSRDMADMLLGDIKNAIAELEKLDFP
TPTRMAQE
3D structure
PDB7x52 Coordinated regulation of Bacteroides thetaiotaomicron glutamate decarboxylase activity by multiple elements under different pH.
ChainE
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 4.1.1.15: glutamate decarboxylase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PLP E F315 S316 F314 S315
BS02 PLP E S123 S124 Q161 T210 D241 A243 H273 K274 S122 S123 Q160 T209 D240 A242 H272 K273
Gene Ontology
Molecular Function
GO:0004351 glutamate decarboxylase activity
GO:0016830 carbon-carbon lyase activity
GO:0016831 carboxy-lyase activity
GO:0030170 pyridoxal phosphate binding
Biological Process
GO:0006536 glutamate metabolic process
GO:0006538 glutamate catabolic process
GO:0019752 carboxylic acid metabolic process
Cellular Component
GO:0005829 cytosol

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Cellular Component
External links
PDB RCSB:7x52, PDBe:7x52, PDBj:7x52
PDBsum7x52
PubMed36358099
UniProtQ8A4M9

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