Structure of PDB 7x4n Chain E

Receptor sequence
>7x4nE (length=332) Species: 6239 (Caenorhabditis elegans) [Search protein sequence]
TCVQVALRIRPQGNREKLEGSRVCTSVLPNDPQVTIGGDRSFTYDHVFDM
PTLQYVVYESCVEKLVDGLFDGYNATVLAYGQTGSGKTHTMGTAFDAAVQ
KEEDLGVIPRAIQHTFRKIAECKAQAIEEPAFEVSVQFVELYNDDVLDLL
SDDRSIRIHEDSRGEIVLHGVEQRSVFDMHGTMDILKNGALNRTVAATNM
NEQSSRSHAIFTLHLKQQRVAEMLCAKFHFVDLAGSERMKRTGATGDRAK
EGISINVGLLALGNVIAALGGVSHVPYRDSKLTRLLQDSLGGNSRTLMIA
CCSPSDSDFVETLNTMKYANRAKEIKNKVVAN
3D structure
PDB7x4n Structural model of microtubule dynamics inhibition by kinesin-4 from the crystal structure of KLP-12 -tubulin complex.
ChainE
Resolution2.88 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.4.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ANP E P14 T86 G87 G89 K90 T91 H92 N213 S216 S217 G264 P11 T83 G84 G86 K87 T88 H89 N201 S204 S205 G235
BS02 MG E T91 S217 D261 T88 S205 D232
Gene Ontology
Molecular Function
GO:0003777 microtubule motor activity
GO:0005524 ATP binding
GO:0008017 microtubule binding
Biological Process
GO:0007018 microtubule-based movement

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Molecular Function
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Biological Process
External links
PDB RCSB:7x4n, PDBe:7x4n, PDBj:7x4n
PDBsum7x4n
PubMed36065637
UniProtG5EGS3|KLP12_CAEEL Kinesin-like protein klp-12 (Gene Name=klp-12)

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