Structure of PDB 7w3m Chain E

Receptor sequence
>7w3mE (length=389) Species: 9606 (Homo sapiens) [Search protein sequence]
MADPRDKALQDYRKKLLEHKEIDGRLKELREQLKELTKQYEKSENDLKAL
QSVGQIVGEVLKQLTEEKFIVKATNGPRYVVGCRRQLDKSKLKPGTRVAL
DMTTLTIMRYLPREVDPLVYNMSHEDPGNVSYSEIGGLSEQIRELREVIE
LPLTNPELFQRVGIIPPKGCLLYGPPGTGKTLLARAVASQLDCNFLKVVS
SSIVDKYIGESARLIREMFNYARDHQPCIIFMDEIDAIGGRRFSEGTSAD
REIQRTLMELLNQMDGFDTLHRVKMIMATNRPDTLDPALLRPGRLDRKIH
IDLPNEQARLDILKIHAGPITKHGEIDYEAIVKLSDGFNGADLRNVCTEA
GMFAIRADHDFVVQEDFMKAVRKVADSKKLESKLDYKPV
3D structure
PDB7w3m USP14-regulated allostery of the human proteasome by time-resolved cryo-EM.
ChainE
Resolution3.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ATP E E134 I135 P176 G177 T178 G179 T181 L182 I312 N339 G340 A341 E134 I135 P176 G177 T178 G179 T181 L182 I312 N339 G340 A341
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
Cellular Component
GO:0000502 proteasome complex

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Molecular Function
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Cellular Component
External links
PDB RCSB:7w3m, PDBe:7w3m, PDBj:7w3m
PDBsum7w3m
PubMed35477760
UniProtA0A087X2I1

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