Structure of PDB 7tid Chain E

Receptor sequence
>7tidE (length=338) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
WVDKYRPKSLNALSHNEELTNFLKSLSDQPRDLPHLLLYGPNGTGKKTRC
MALLESIFGPGVYRLKIDVRQFVTASNRKLELNVVSSPYHLEITPSDMGN
NDRIVIQELLKEVAQMEHRYKCVIINEANSLTKDAQAALRRTMEKYSKNI
RLIMVCDSMSPIIAPIKSRCLLIRCPAPSDSEISTILSDVVTNERIQLET
KDILKRIAQASNGNLRVSLLMLESMALNNELALKSSSPIIKPDWIIVIHK
LTRKIVKERSVNSLIECRAVLYDLLAHCIPANIILKELTFSLLDVETLNT
TNKSSIIEYSSVFDERLSLGNKAIFHLEGFIAKVMCCL
3D structure
PDB7tid Cryo-EM structures reveal high-resolution mechanism of a DNA polymerase sliding clamp loader.
ChainE
Resolution3.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna E N103 N104 N336 N100 N101 N321
BS02 AGS E E159 R184 E144 R169
BS03 ADP E V5 R9 P10 L16 S17 H18 N45 G46 G48 K49 K50 T51 V2 R6 P7 L13 S14 H15 N42 G43 G45 K46 K47 T48
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003689 DNA clamp loader activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
Biological Process
GO:0000077 DNA damage checkpoint signaling
GO:0006260 DNA replication
GO:0006261 DNA-templated DNA replication
GO:0006271 DNA strand elongation involved in DNA replication
GO:0006272 leading strand elongation
GO:0006281 DNA repair
GO:0007062 sister chromatid cohesion
GO:0007064 mitotic sister chromatid cohesion
GO:0090618 DNA clamp unloading
Cellular Component
GO:0005634 nucleus
GO:0005663 DNA replication factor C complex
GO:0031389 Rad17 RFC-like complex
GO:0031390 Ctf18 RFC-like complex
GO:0031391 Elg1 RFC-like complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7tid, PDBe:7tid, PDBj:7tid
PDBsum7tid
PubMed35179493
UniProtP38251|RFC5_YEAST Replication factor C subunit 5 (Gene Name=RFC5)

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