Structure of PDB 7tc8 Chain E

Receptor sequence
>7tc8E (length=511) Species: 414 (Methylococcus capsulatus) [Search protein sequence]
ANRAPTSVNAQEVHRWLQSFNWDFKNNRTKYATKYKMANETKEQFKLIAK
EYARMEAVKDERQFGSLQDALTRLNAGVRVHPKWNETMKVVSNFLEVGEY
NAIAATGMLWDSAQAAEQKNGYLAQVLDEIRHTHQCAYVNYYFAKNGQDP
AGHNDARRTRTIGPLWKGMKRVFSDGFISGDAVECSLNLQLVGEACFTNP
LIVAVTEWAAANGDEITPTVFLSIETDELRHMANGYQTVVSIANDPASAK
YLNTDLNNAFWTQQKYFTPVLGMLFEYGSKFKVEPWVKTWNRWVYEDWGG
IWIGRLGKYGVESPRSLKDAKQDAYWAHHDLYLLAYALWPTGFFRLALPD
QEEMEWFEANYPGWYDHYGKIYEEWRARGCEDPSSGFIPLMWFIENNHPI
YIDRVSQVPFCPSLAKGASTLRVHEYNGQMHTFSDQWGERMWLAEPERYE
CQNIFEQYEGRELSEVIAELHGLRSDGKTLIAQPHVRGDKLWTLDDIKRL
NCVFKNPVKAF
3D structure
PDB7tc8 Batch Production of High-Quality Graphene Grids for Cryo-EM: Cryo-EM Structure of Methylococcus capsulatus Soluble Methane Monooxygenase Hydroxylase.
ChainE
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.14.13.25: methane monooxygenase (soluble).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FE E E144 E209 E243 H246 E129 E194 E228 H231
BS02 FE E E114 E144 H147 E99 E129 H132
Gene Ontology
Molecular Function
GO:0004497 monooxygenase activity
GO:0005515 protein binding
GO:0015049 methane monooxygenase [NAD(P)H] activity
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding
Biological Process
GO:0006730 one-carbon metabolic process

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Molecular Function
View graph for
Biological Process
External links
PDB RCSB:7tc8, PDBe:7tc8, PDBj:7tc8
PDBsum7tc8
PubMed36926824
UniProtP22869|MEMA_METCA Methane monooxygenase component A alpha chain (Gene Name=mmoX)

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