Structure of PDB 7tan Chain E

Receptor sequence
>7tanE (length=97) Species: 9606 (Homo sapiens) [Search protein sequence]
PHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSS
AVMALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGER
3D structure
PDB7tan Multivalent DNA and nucleosome acidic patch interactions specify VRK1 mitotic localization and activity.
ChainE
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna E R40 V46 R49 R69 R3 V9 R12 R32
BS02 dna E R42 R72 R83 F84 V117 T118 R5 R35 R46 F47 V80 T81
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Biological Process
GO:0006325 chromatin organization
GO:0006334 nucleosome assembly
Cellular Component
GO:0000786 nucleosome
GO:0005576 extracellular region
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome
GO:0070062 extracellular exosome

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Cellular Component
External links
PDB RCSB:7tan, PDBe:7tan, PDBj:7tan
PDBsum7tan
PubMed35390161
UniProtQ71DI3|H32_HUMAN Histone H3.2 (Gene Name=H3C15)

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