Structure of PDB 7sg2 Chain E

Receptor sequence

>7sg2E (length=242) Species: 9606 (Homo sapiens) [Search protein sequence]

AVISQKPSRDICQRGTSLTIQCQVDSQVTMMFWYRQQPGQSLTLIATANQ
GSEATYESGFVIDKFPISRPNLTFSTLTVSNMSPEDSSIYLCSVALGSDT
GELFFGEGSRLTVLEDLKNVFPPEVAVFEPSEAEISHTQKATLVCLATGF
FPDHVELSWWVNGKEVHSGVCTDPQPLKEQPALNDSRYALSSRLRVSATF
WQNPRNHFRCQVQFYGLSENDEWTQDRAKPVTQIVSAEAWGR

3D structure

PDB

7sg2 Structural basis of T cell receptor specificity and cross-reactivity of two HLA-DQ2.5-restricted gluten epitopes in celiac disease.

Chain

Resolution

3.1 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	E	Q28 T37 L108 S110	Q27 T29 L96 S98
BS02	CA	E	D11 I12 S231 D234	D10 I11 S218 D221

External links

PDB	RCSB:7sg2, PDBe:7sg2, PDBj:7sg2
PDBsum	7sg2
PubMed	35065967

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