Structure of PDB 7s4g Chain E

Receptor sequence

>7s4gE (length=208) Species: 9606 (Homo sapiens) [Search protein sequence]

VQLVQSGAEVKKPGASVKVSCKASGYTFTTYVMHWVRQAPGQGLEWMGYI
NPYNDGTKYNEKFKGRVTMTRDTSISTAYMELSRLRSDDTAVYYCGRRNF
DYWGQGTLVTVSSASTKGPSVFPLAPSGTAALGCLVKDYFPEPVTVSWNS
GALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTK
VDKKVEPK

3D structure

PDB

7s4g Novel Anti-LY6G6D/CD3 T-Cell-Dependent Bispecific Antibody for the Treatment of Colorectal Cancer.

Chain

Resolution

2.2 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	E	Y32 V33 K59 R99 N100	Y31 V32 K58 R98 N99

External links

PDB	RCSB:7s4g, PDBe:7s4g, PDBj:7s4g
PDBsum	7s4g
PubMed	35364611

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