Structure of PDB 7rsc Chain E

Receptor sequence
>7rscE (length=187) Species: 9606 (Homo sapiens) [Search protein sequence]
STFSKLREQLGPVTQEFWDNLEKETEGLRQEMSKDLEEVKAKVQPYLDDF
QKKWQEEMELYRQKVEPLRAELQEGARQKLHELQEKLSPLGEEMRDRARA
HVDALRTHLAPYSDELRQRLAARLEALKENGGARLAEYHAKATEHLSTLS
EKAKPALEDLRQGLLPVLESFKVSFLSALEEYTKKLN
3D structure
PDB7rsc Oncogenic KRAS G12D mutation promotes dimerization through a second, phosphatidylserine-dependent interface: a model for KRAS oligomerization.
ChainE
ResolutionN/A
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 7Q9 E S667 R671 S113 R117
BS02 7Q9 E V619 R623 R631 V65 R69 R77
BS03 7Q9 E L634 Q638 L80 Q84
BS04 7Q9 E L601 Q605 L47 Q51
BS05 7Q9 E L733 Y736 T737 L179 Y182 T183
BS06 7Q9 E E591 K594 E37 K40
BS07 7Q9 E A630 R631 K633 L634 A76 R77 K79 L80
Gene Ontology
Biological Process
GO:0006869 lipid transport
GO:0042157 lipoprotein metabolic process
Cellular Component
GO:0005576 extracellular region

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External links
PDB RCSB:7rsc, PDBe:7rsc, PDBj:7rsc
PDBsum7rsc
PubMed34703570
UniProtP02647|APOA1_HUMAN Apolipoprotein A-I (Gene Name=APOA1)

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