Structure of PDB 7rga Chain E

Receptor sequence
>7rgaE (length=270) Species: 32630 (synthetic construct) [Search protein sequence]
HHHHSNPSLIRSESWHVYDGNEANLLDGDDNTGVWYKRSNGEASLAGEFI
GLDLGKEIKLDGIRFVIGKNGGGSSDKWNKFKLEYSLDNESWTTIKEYDK
TGAPAGKDVIEESFETPISAKYIRLTNLEPRHVQLTFSEFAIVSDSQVQL
VESGGGLVQAGGSLRLSCAASRRSSRSWAMAWFRQAPGKEREFVAKISGD
GRLTTYGDSVKGRFTISRDNAEYLVYLQMDSLKPEDTAVYYCAADDNYVT
ASWRSGPDYWGQGTQVTVSS
3D structure
PDB7rga Design of a methotrexate-controlled chemical dimerization system and its use in bio-electronic devices.
ChainE
Resolution2.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.2.1.35: hyaluronoglucosaminidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MTX E L178 S202 M208 R246 D247 Y251 L252 V253 Y287 L150 S174 M180 R218 D219 Y223 L224 V225 Y259
BS02 MTX E T96 G97 A98 P99 T101 G102 A103 P104
External links
PDB RCSB:7rga, PDBe:7rga, PDBj:7rga
PDBsum7rga
PubMed34880210
UniProtP26831|NAGH_CLOPE Hyaluronoglucosaminidase (Gene Name=nagH)

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