Structure of PDB 7q8s Chain E

Receptor sequence
>7q8sE (length=359) Species: 5664 (Leishmania major) [Search protein sequence]
SSIVCDNGSGMVKAGFSGDDAPRHVFPSIVGRPKKTVYVGDEAQSKRGVL
SLKYPIEHGIVTNWDDMEKIWHHTFYNELRVNPEQHNVLLTEAPMNPKQN
REKMTQIMFETFNVPSLYIGIQAVLSLYSSGRTTGIVLDAGDGVTHTVPI
YEGYSLPHAVRRVDMAGRDLTEYLMKIMMETGTTFTTTAEKEIVRNVKEQ
LCYVALDFEEEMTNSAKSANEEAFELPDGNVMMVGNQRFRCPEVLFKPSL
IGLDEAPGFPEMVYQSINKCDIDVRRELYGNIVLSGGSTMFLNLPERLAK
EISNLAPSSIKPKVVAPPERKYSVWIGGSILSSLTTFQTMWVKKSEYDES
GPSIVHNKC
3D structure
PDB7q8s Structural basis of rapid actin dynamics in the evolutionarily divergent Leishmania parasite.
ChainE
Resolution3.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.4.-
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ADP E S14 G15 G156 D157 K213 E214 G302 F306 K336 S9 G10 G141 D142 K198 E199 G287 F291 K321
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016787 hydrolase activity
Cellular Component
GO:0005737 cytoplasm
GO:0005856 cytoskeleton

View graph for
Molecular Function

View graph for
Cellular Component
External links
PDB RCSB:7q8s, PDBe:7q8s, PDBj:7q8s
PDBsum7q8s
PubMed35705539
UniProtP45520|ACT_LEIMA Actin

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