Structure of PDB 7q6r Chain E

Receptor sequence
>7q6rE (length=390) Species: 1890 (Streptomyces antibioticus) [Search protein sequence]
VPAYPFSLPHALDLDPHYAELRRDEPVSRVRLPYGEGTAWLVTRMSDARI
VLGDSRFSTAAATDPATPRMFPTPPYPDGVLAQDPPDHTRLRRLVGKAFT
ARRVEEMRPRVRSLVDSLLDDMVAHGSPADLVEFLAVPFPVAVICELLGV
PLEDRDLFRTFSDAMLSSTRLTAAEIQRVQQDFMVYMDGLVAQRREDLLG
ALALATDNDDHLTKGEIVNMGVSLLIAGHETSVNQITNLVHLLLTERKRY
ESLVADPALVPAAVEEMLRYTPLVSAGSFVRVATEDVELSTVTVRAGEPC
VVHFASANRDEEVFDHADELDFHRERNPHIAFGHGAHHCIGAQLGRLELQ
EALSALVRRFPTLDLAEPVAGLKWKQGMLIRGLERQIVSW
3D structure
PDB7q6r Point Mutations at a Key Site Alter the Cytochrome P450 OleP Structural Dynamics.
ChainE
Resolution2.44 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 HEM E V93 L94 H101 R105 F112 A244 G245 T248 R298 A348 F349 H354 C356 I357 G358 V80 L81 H88 R92 F99 A227 G228 T231 R281 A331 F332 H337 C339 I340 G341
BS02 DEB E F84 L179 L396 F71 L166 L379
Gene Ontology
Molecular Function
GO:0004497 monooxygenase activity
GO:0005506 iron ion binding
GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0020037 heme binding
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:7q6r, PDBe:7q6r, PDBj:7q6r
PDBsum7q6r
PubMed35053203
UniProtQ59819

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