Structure of PDB 7pds Chain E

Receptor sequence

>7pdsE (length=453) Species: 1280 (Staphylococcus aureus) [Search protein sequence]

NDWKSQLRRSATTQALKKTTTNAEIILCNDESLKGLVQYDAFEKVTKLKR
LPYWRSKGDANYYWADIDTTHVISHIDKLYNVQFSRDLIDTVIEKEAYQN
RFHPIKSMIESKSWDGIKRIETLFIDYLGAEDNHYNREVTKKWMMGAVAR
IYQPGIKYDSMIILYGGQGVGKSTAVSKLGGHWYNQSIKTFKGDEVYKKL
QGSWICEIEELSAFQKSTIEDIKGFISAIVDIYRASYGKRTERHPRQCVF
VGTTNNYEFLKDQTGNRRFFPITTDKNKATKSPFDDLTPVVVQQMFAEAR
VYFDENPTDKALLLDKEASEMALKVQEAHSEKDALVGEIEEFLERPIPSD
YWYRTLEEKRVSAHDVIDDYIKLGDGKLIEKPGAYVWRDKVCSMEIWKVM
MKRDDQPQQHHLRKIDKALRNTNYCGTVKKQTRYGEGIGKQYGFSVDLAS
YYK

3D structure

PDB

7pds Staphylococcal self-loading helicases couple the staircase mechanism with inter domain high flexibility.

Chain

Resolution

3.14 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	dna	E	R248 S250 Y251	R234 S236 Y237
BS02	AGS	E	K171 R281 R282 D323 K324 L327	K157 R267 R268 D309 K310 L313
BS03	AGS	E	Q182 G183 G185 K186 S187 T188 F298	Q168 G169 G171 K172 S173 T174 F284

External links

PDB	RCSB:7pds, PDBe:7pds, PDBj:7pds
PDBsum	7pds
PubMed	35871290
UniProt	Q8VLX1

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