Structure of PDB 7pbi Chain E

Receptor sequence

>7pbiE (length=523) Species: 979746 (Gulosibacter chungangensis)

TLPDGVSAEQFANAISEFSETIGSEYVRVDEATVSEYDDKFPVTDGDEFK
GSAVIWPGSTEDVQVIVRIANKYGIPLHAFSGGRNLGYGGSSPMLTGTVL
LHLGKRMNRVLEINEKLAYAVVEPGVDYKTLYEAVRDSGAKLMIDPAELD
WGSVMGNTMEHGVGYTPYADHSMWRCGMEVVLADGEVLRTGMGGLPGSEA
WHLYPGQLGPSIEGLFEQSNFGICTRMGMQLMPTPPEMLSFAIYFENEDD
LPAIMETTLPLRIGMAPLQAAPIVRNVTFDAACVSKREEWQTEPGPLTDE
AKQRMVDELGIGHWIVYGTCYGPRWQIDKYIEMIRDAYLQIPGARFETNE
TLPLREGDRASELLNARHELNTGVPNRHSAAVFDWFPNAGHFFYAPVSAP
SGEDAAKQYEDTKRISDDHGIDYLAQFIIGLREMHHICLPLYDTADPASR
KETLDMTRELIRAGAEEGYGIYRAHNVLADQVAETYSFNNHIQRRSHERI
KDALDPNGILNPGKSGIWPERLR

3D structure

• PDB: 7pbi Discovery, Biocatalytic Exploration and Structural Analysis of a 4-Ethylphenol Oxidase from Gulosibacter chungangensis.
• Chain: E
• Resolution: 2.8 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	FAD	E	H82 F84 S85 G86 G87 R88 N89 E152 G156 S157 G160 N161 M163 E164 G166 V167 I227 C228 H395 F397 R477 K518	H78 F80 S81 G82 G83 R84 N85 E148 G152 S153 G156 N157 M159 E160 G162 V163 I223 C224 H391 F393 R473 K514
BS02	H7Y	E	Y92 V167 R279 F283 F397 I441 Y476	Y88 V163 R275 F279 F393 I437 Y472

Gene Ontology

Molecular Function

• GO:0000166 nucleotide binding
• GO:0003824 catalytic activity
• GO:0004458 D-lactate dehydrogenase (cytochrome) activity
• GO:0008720 D-lactate dehydrogenase activity
• GO:0050660 flavin adenine dinucleotide binding
• GO:0071949 FAD binding

Biological Process

• GO:1903457 lactate catabolic process

External links

• PDB: RCSB:7pbi, PDBe:7pbi, PDBj:7pbi
• PDBsum: 7pbi
• PubMed: 34523783
• UniProt: A0A7J5BGR1