Structure of PDB 7pb2 Chain E

Receptor sequence

>7pb2E (length=244) Species: 9606 (Homo sapiens) [Search protein sequence]

NAGVTQTPKFRVLKTGQSMTLLCAQDMNHEYMYWYRQDPGMGLRLIHYSV
GEGTTAKGEVPDGYNVSRLKKQNFLLGLESAAPSQTSVYFCASSYGPGQH
NSPLHFGNGTRLTVTEDLNKVFPPEVAVFEPSEAEISHTQKATLVCLATG
FYPDHVELSWWVNGKEVHSGVCTDPQPLKEQPALNDSRYALSSRLRVSAT
FWQDPRNHFRCQVQFYGLSENDEWTQDRAKPVTQIVSAEAWGRA

3D structure

PDB

7pb2 Therapeutic high affinity T cell receptor targeting a KRASG12D cancer neoantigen

Chain

Resolution

3.41 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	E	G98 Q99 H100	G98 Q99 H100

External links

PDB	RCSB:7pb2, PDBe:7pb2, PDBj:7pb2
PDBsum	7pb2
PubMed

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