Structure of PDB 7p4b Chain E

Receptor sequence
>7p4bE (length=260) Species: 9606 (Homo sapiens) [Search protein sequence]
GSHSLKYFHTSVSRPGRGEPRFISVGYVDDTQFVRFDNDAASPRMVPRAP
WMEQEGSEYWDRETRSARDTAQIFRVNLRTLRGYYNQSEAGSHTLQWMHG
CELGPDGRFLRGYEQFAYDGKDYLTLNEDLRSWTAVDTAAQISEQKSNDA
SEAEHQRAYLEDTCVEWLHKYLEKGKETLLHLEPPKTHVTTLRCWALGFY
PAEITLTWQQDQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHE
GLPEPVTLRW
3D structure
PDB7p4b Primary and secondary functions of HLA-E are determined by stability and conformation of the peptide-bound complexes.
ChainE
Resolution1.72 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide E I73 D149 A150 I73 D149 A150
BS02 peptide E Y7 E63 A67 T70 N77 Y84 W97 S143 K146 H155 Q156 Y159 W167 Y171 Y7 E63 A67 T70 N77 Y84 W97 S143 K146 H155 Q156 Y159 W167 Y171
BS03 ZN E H181 E183 H181 E183
External links
PDB RCSB:7p4b, PDBe:7p4b, PDBj:7p4b
PDBsum7p4b
PubMed35705051
UniProtP13747|HLAE_HUMAN HLA class I histocompatibility antigen, alpha chain E (Gene Name=HLA-E)

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