Structure of PDB 7p49 Chain E

Receptor sequence
>7p49E (length=266) Species: 9606 (Homo sapiens) [Search protein sequence]
GSHSLKYFHTSVSRPGRGEPRFISVGYVDDTQFVRFDNDAASPRMVPRAP
WMEQEGSEYWDRETRSARDTAQIFRVNLRTLRGYYNQSEAGSHTLQWMHG
CELGPDGRFLRGYEQFAYDGKDYLTLNEDLRSWTAVDTAAQISEQKSNDA
SEAEHQRAYLEDTCVEWLHKYLEKGKETLLHLEPPKTHVTHHPISDHEAT
LRCWALGFYPAEITLTWQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYT
CHVQHEGLPEPVTLRW
3D structure
PDB7p49 Primary and secondary functions of HLA-E are determined by stability and conformation of the peptide-bound complexes.
ChainE
Resolution2.05 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide E Y7 R62 E63 S66 A67 I73 N77 Y84 E114 F116 S143 K146 E152 H155 Y159 T163 W167 Y171 Y7 R62 E63 S66 A67 I73 N77 Y84 E114 F116 S143 K146 E152 H155 Y159 T163 W167 Y171
BS02 ZN E H181 E183 H181 E183
External links
PDB RCSB:7p49, PDBe:7p49, PDBj:7p49
PDBsum7p49
PubMed35705051
UniProtP13747|HLAE_HUMAN HLA class I histocompatibility antigen, alpha chain E (Gene Name=HLA-E)

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