Structure of PDB 7ow6 Chain E

Receptor sequence

>7ow6E (length=245) Species: 9606 (Homo sapiens) [Search protein sequence]

MNAGVTQTPKFRVLKTGQSMTLLCAQDMNHEYMYWYRQDPGMGLRLIHYS
VGEGTTAKGEVPDGYNVSRLKKQNFLLGLESAAPSQTSVYFCASKVGPGQ
HNSPLHFGNGTRLTVTEDLNKVFPPEVAVFEPSEAEISHTQKATLVCLAT
GFYPDHVELSWWVNGKEVHSGVCTDPQPLKEQPALNDSRYALSSRLRVSA
TFWQDPRNHFRCQVQFYGLSENDEWTQDRAKPVTQIVSAEAWGRA

3D structure

PDB

7ow6 Therapeutic high affinity T cell receptor targeting a KRASG12D cancer neoantigen

Chain

Resolution

2.64 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	E	G98 Q99 H100 N101	G99 Q100 H101 N102

External links

PDB	RCSB:7ow6, PDBe:7ow6, PDBj:7ow6
PDBsum	7ow6
PubMed

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