Structure of PDB 7n6s Chain E

Receptor sequence
>7n6sE (length=147) Species: 272947 (Rickettsia prowazekii str. Madrid E) [Search protein sequence]
TIIEVKIKKLENFLGNLPEYATEHSAGMDLVAANEQSITIKVGSIQLIPT
GIAIALPESFEAQIRPRSGLAVKHGITVANSPGTIDADYRGEIKVLLINL
GNKDFIIEKGMRIAQMIIAKYERVLWAETSILTETMRGRGGFGSTGL
3D structure
PDB7n6s Crystal Structure of deoxyuridine 5'-triphosphate nucleotidohydrolase from Rickettsia prowazekii str. Madrid E in complex with 2'-deoxyuridine 5'-monophoephate (dUMP)
ChainE
Resolution1.75 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.1.23: dUTP diphosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 UMP E N81 T85 I86 D87 Y90 K95 N80 T84 I85 D86 Y89 K94
BS02 UMP E R68 S69 R67 S68
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0004170 dUTP diphosphatase activity
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
Biological Process
GO:0006226 dUMP biosynthetic process
GO:0009117 nucleotide metabolic process
GO:0046081 dUTP catabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:7n6s, PDBe:7n6s, PDBj:7n6s
PDBsum7n6s
PubMed
UniProtQ9ZDD2|DUT_RICPR Deoxyuridine 5'-triphosphate nucleotidohydrolase (Gene Name=dut)

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