Structure of PDB 7mj1 Chain E

Receptor sequence
>7mj1E (length=211) Species: 220668 (Lactiplantibacillus plantarum WCFS1) [Search protein sequence]
ANVDLDRQRRNGFPEVIYGAGKTATQIVGIVQALSQQTLPILTTRLSAEK
FAALQPALPTAVYHATAQCMTVGEQPAPKTPGYIAVVTAGTSDQPVAEEA
AVTAETFGNRVERVYDVGVAGIHRLFAKLDVIRGARVVIVIAGMEGALAS
VVGGLVDKPVIAVPTSVGYGTSFQGMTALLTMLNSCASGITVVNIDNGFG
AAYSASMVNQM
3D structure
PDB7mj1 The LarB carboxylase/hydrolase forms a transient cysteinyl-pyridine intermediate during nickel-pincer nucleotide cofactor biosynthesis.
ChainE
Resolution3.402 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.5.1.143: pyridinium-3,5-biscarboxylic acid mononucleotide synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAI E A124 G125 T126 S127 D128 V154 A177 G178 M179 A182 L183 A89 G90 T91 S92 D93 V119 A142 G143 M144 A147 L148
Gene Ontology
Molecular Function
GO:0016740 transferase activity
GO:0016787 hydrolase activity
Biological Process
GO:0006189 'de novo' IMP biosynthetic process
Cellular Component
GO:0005886 plasma membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7mj1, PDBe:7mj1, PDBj:7mj1
PDBsum7mj1
PubMed34548397
UniProtF9UST0|LARB_LACPL Pyridinium-3,5-biscarboxylic acid mononucleotide synthase (Gene Name=larB)

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