Structure of PDB 7m8q Chain E

Receptor sequence
>7m8qE (length=515) Species: 595536 (Methylosinus trichosporium OB3b) [Search protein sequence]
DALKVNRAPVGVEPQEVHKWLQSFNWDFKENRTKYPTKYHMANETKEQFK
VIAKEYARMEAAKDERQFGTLLDGLTRLGAGNKVHPRWGETMKVISNFLE
VGEYNAIAASAMLWDSATAAEQKNGYLAQVLDEIRHTHQCAFINHYYSKH
YHDPAGHNDARRTRAIGPLWKGMKRVFADGFISGDAVECSVNLQLVGEAC
FTNPLIVAVTEWASANGDEITPTVFLSVETDELRHMANGYQTVVSIANDP
ASAKFLNTDLNNAFWTQQKYFTPVLGYLFEYGSKFKVEPWVKTWNRWVYE
DWGGIWIGRLGKYGVESPASLRDAKRDAYWAHHDLALAAYAMWPLGFARL
ALPDEEDQAWFEANYPGWADHYGKIFNEWKKLGYEDPKSGFIPYQWLLAN
GHDVYIDRVSQVPFIPSLAKGTGSLRVHEFNGKKHSLTDDWGERQWLIEP
ERYECHNVFEQYEGRELSEVIAEGHGVRSDGKTLIAQPHTRGDNLWTLED
IKRAGCVFPDPLAKF
3D structure
PDB7m8q Soluble Methane Monooxygenase Component Interactions Monitored by 19 F NMR.
ChainE
Resolution2.08 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.14.13.25: methane monooxygenase (soluble).
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 FE E E114 E144 H147 E103 E133 H136
BS02 FE E E144 E209 E243 H246 E133 E198 E232 H235
Gene Ontology
Molecular Function
GO:0004497 monooxygenase activity
GO:0015049 methane monooxygenase [NAD(P)H] activity
GO:0046872 metal ion binding
Biological Process
GO:0006730 one-carbon metabolic process

View graph for
Molecular Function

View graph for
Biological Process
External links
PDB RCSB:7m8q, PDBe:7m8q, PDBj:7m8q
PDBsum7m8q
PubMed34100595
UniProtP27353|MEMA_METTR Methane monooxygenase component A alpha chain (Gene Name=mmoX)

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